WG D: Models and Tools for Risk Assessment

Chair: Tommaso Serchi, LIST (tommaso.serchi@list.lu)

Co-chairs: Wouter Fransman, TNO (wouter.fransman@tno.nl) 


Working Group D originates from the two former working groups on Risk (WG5 in the old structure)and Modelling (WG6 in the old structure)and covers a large number of topics related to the modelling and quantification of the risk associated to the use of nano-materials, along their entire life cycle (from cradle to grave) for humans (workers and consumers) and for the environment. WG-D will also deal with the regulatory aspects of nano-materials risk assessment and with development and validation of models and tools for human/environmental risk assessment.

WG-D is closely linked and will close work together with the new WG-C on “Exposure & Hazard assessment”.

We envisage a new Working Group that combines knowledge from several groups of experts, i.e.:

  1. Human risk assessment (occupational exposure and consumers’ exposure).
  2. Environmental risk assessment.
  3. Regulatory aspects of Risk assessment.
  4. Development of models and tools for risk assessment.
  5. Impact assessment and Life Cycle Analysis of nano-materials.

This will result in the creation of various teams, each with their own webpages, members, and collaborations. We would like to keep as much as possible the ongoing initiatives from the old WGs 2 and 3 and build from that basis to further extend the exchange of knowledge across projects, institutes and countries.


Additional €2M added to the budget pot covering the NMBP-13 and NMBP-14 call topics, to support OECD nanosafety standardisation (the Malta project) 

The total budget for the NMBP-13 and NMBP-14 topics is now €30 Million, with an expected split of approximately €12 M for NMBP-13 (Risk Governance) and €18 M for NMBP-14 (nanoinformatics).  Note that more than 1 project is expected to be funded for each topic.

The Risk Governance calls should include some provisions (i.e. a Workpackage) detailing how the NMBP-13 project will support the wider group of NSC projects to feed their protocols and standardisation activities into the ongoing OCED-led revision of TG/GDs for nanomaterials safety assessment in light of the REACH amendments for nanomaterials, specifically focussing on supporting the organisation of expert meetings on key topics related to the standards under development / revision  (i.e. the Malta project).  The NMBP-13 project budget can be increased from the suggestion in the call fiche to account for these additional OECD-supporting activities.

If you are coordinating a proposal on this topic, please contact your country-representatives for the OECD (http://www.oecd.org/chemicalsafety/nanosafety/sponsors-testing-programme-manufactured-nanomaterials.htm) for more details on the priority TGs/GDs relevant to nanomaterials being revised, the lead countries sponsoring each, and the timetable for activities.

WG Structure

Sub-group on Human risk assessment – Keld Alstrup Jensen (NRCWE)

Sub-group on Environmental risk assessment -

Sub-group on Predictive computational models for risk assessment -

Sub-group on Impact assessment and LCA

Sub-group on Regulatory aspects – Maria Dusinska (NILU, Norvey)

General aims and objectives

  • To promote development of solutions for the evaluation of the risk associated, for humans and for the environment, with the production, use and disposal of nano-materials (in close collaboration with WG C – “Exposure & Hazard assessment”).
  • To encourage the sharing of knowledge and methods generated within the different projects.
  • To promote the progresses achieved in the field to relevant stakeholders and regulatory bodies, with the final objective of reaching regulatory acceptancy (in close cooperation with WG E – “Safer by Design, Innovation and Regulation”). 
  • Gather information on existing models for risk assessment.
  • Understand the limitation and gaps of existing methodologies for risk assessment of nano-materials.
  • Development of a road-map for the regulatory acceptancy of risk assessment models.

Prospective coordination actions

Coordination in the communication and dissemination of results and activities soming from running/planned projects in the area of nano-materials’ risk assessment.