This document on the strategic priorities of nanosafety research during 2015-2025 has been produced as a joint effort of the European NanoSafety Cluster, a forum incorporating FP6 and FP7 funded nanosafety research projects. It also includes several nanosafety research projects, that have been funded by different EU Member States It identifies four major areas of research would greatly benefit our current understanding of ENM features, exposure to them, hazard mechanisms of ENM, as well as their risk assessment and management. Hence, the strategic vision on the future directions of European nanosafety research presented in this document may have a major impact on the future nanosafety research within and outside the European Union, and consequently, on the success of nanotechnologies.

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