Nanotechnology-enabled products are rapidly entering the market and the environment, which necessitates efficient hazard and risk assessments. However, the current slow and costly animal-based testing with limited capacity cannot meet the needs of industry and regulators. Therefore, the EU-funded nanoPASS project will design cost-efficient high-throughput screening approaches for inhalation-related long-term hazards. It proposes a shift of testing focus from late endpoints to early key events leading to adverse outcomes. The early events will be identified by key bridging methods: intravital in vivo microscopy, quantitative time-lapse in vitro microscopies and automated identification of the modes of action. The real-life applicability of developed tests will be demonstrated by performing risk assessment in production and recycling facilities and devising a risk mitigation plan.
1 January 2023 – 31 December 2026
Contact
- Project Coordinator: JoĹľef Stefan Institute
- Project website: https://nanopass.eu/
- E-mail: contact@nanopass.eu