Hazard WG

The working group

Chair: Flemming R. Cassee, RIVM, The Netherlands. NanoMile, NanoReg, NanoImpactnet (deputy- coordinator) and ENPRA (member) 

Co-chair: Teresa Fernandez, Heriot Watt University, Edinburgh, UK

 

 Download recent progress overview as presented on 26 Feb 2012 in Prague during the NSC meeting

What we wish to do

  • Information exchange of methods available within the Cluster
  • Harmonised methods/requirements for kinetic investigation
  • Harmonised methods/requirements for appropriate toxicological endpoints
  • Harmonised methods/requirements for appropriate in vitro tests (e.g. cell lines)
  • Harmonised protocols for testing if appropriate
  • Comparison in-vitro versus in-vivo results
  • Validation of appropriate testing methods including identification of limitations
  • Requirements for screening tests
  • Description of correlation between biological effects and material properties (cooperation Working Group 1)
  • Description of correlation between bioavailability/bioaccumulation/ADME and NP properties (cooperation Working Group 1)
  • Description of correlation between biological effects and exposure aspects and LCA (cooperation Working Group 3)
  • Provision of results and outcome to the database (cooperation Working Group 4)

 


 

Focus groups and tasks

This working group covers a large number of topics. This has lead and will result in the creation of various teams, each with their own webpages and members (see menu)

 

Task

Who

When

Set up a online submission system to faciliate rapid and easy exchange of information

Flemming withNSCwebsite manager

Dec 2012

Workshop significance of biomembranes in nanotoxicology

Andrew Nelson

March 2012

Report risk-oriented ecotoxicological study in the marine environment

Ilaria Corsi

December 2012

Workshop on Nano-immunosafety within the International Congress of Immunology in 2013 in Rome

Diana Boraschi

2013

Dissemination of results (reports)

Teresa Fernandeze with WG7 members

December 2012

Review of the status of current physiologically based pharmacokinetic modeling approaches applied in toxicology a

Dave Spurgeon

December 2012

Contributions to Nanosafety:Strategic 
Research Agenda towards Safe and 
Sustainable Nanomaterial and 
Nanotechnology Innovations

Flemming Cassee, Teresa Fernandes an others

Until May 2013

Symposium on Safety issues and regulatory challenges of nanomaterials

Socorro Vázquez-Campos (NANOPOlYTOX), Sergio Moya (HINAMOX), Maria Blázquez (NEPHH), Lang Tran (ENPRA) and Juan Riego Sintes (JRC)

May 2012